BETTER4U aims to unveil the interplay between obesity biological and lifestyle determinants. The project aims at closing the current gap between research and effective personalized interventions for obesity prevention, via use of modern monitoring tools and artificial intelligence and machine learning practices. The purpose of this deliverable is to provide a detailed description of the proceedings of the project’s kick-off meetings, held in Athens, Greece, on November 2nd and 3rd 2023, with the combined in-person and online participation of the 28 international and multidisciplinary consortium partners from Europe, Israel and Australia (20 in-person and 8 online team attendances). During this two-day meeting, HUA presented the scientific basis and organizational structure of the project, each leader presented the proceedings that are outlined in their corresponding work package and action points on next steps were jointly discussed and agreed.